Mahbuba Yesmin*, M. A. Jalil Chowdhury, Nirmol Kumar Biswas, Afroza Alam
Aim: Clinical trials consistently showed kidney protective effects of proteinuria reduction. The endeavour in this study was to see whether the degree of proteinuria was related to the progressive stages of chronic kidney disease. Methods: This Observational study was carried out on a total of 100 patients above 18 years of either sex with chronic kidney disease in the Department of Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka. Data were collected through semi-structured questionnaire. Students t- Test and Chi-square (χ2 ) tests were done, and p value <0.05 was considered significant. Results: The mean eGFR for the study population was 16.74 ± 12.92 ml/min/1.73 m2 . The mean eGFR was 40.44 ± 7.88 ml/min/1.73 m2 , 21.22 ± 3.27 ml/min/1.73 m2 and 6.69 ± 2.73 ml/min/1.73 m2 in stage 3, stage 4 and stage 5 respectively. The overall range of proteinuria was from 1+ to 2+ in stage 3, from 2+ to 4+ in stage 4 and from 3+ to 4+ in stage 5. For 1+ proteinuria mean eGFR was 43.9 ± 12.08 ml/min/1.73 m2 (stage 3), for 2+ proteinuria mean GFR was 21.2 ± 8.52 ml/min/1.73 m2 (stage 4) and for 3+ proteinuria mean GFR was 9.4 ± 7.03 ml/min/1.73 m2 (stage 5). eGFR in subjects with 3+≤ proteinuria was significantly lower than that in subjects with 2+ ≤ proteinuria.