Alka Dubey, Shashi Prabha Agarwal, Neelesh Yadav and Rajnish Kumar
MicroRNA (miRNA) are a class of small regulatory non coding RNAs. These are about 21 to 25 nucleotides in length. Analysis of miRNA is leading to new paradigms for control of gene expression during plants and animals. Most noncoding RNAs are characterized by a specific secondary structures that determine their function. In present study we determine the minimum free energy (MFE) of C. elegans precursor’s sequences. That retrieves from mirBASE.