Aarav Mehta
Metabolic flexibility refers to the body's ability to adapt fuel oxidation to fuel availability, allowing for the efficient use of energy substrates such as carbohydrates and fats. It is a critical determinant of metabolic health and is implicated in the development of various metabolic disorders, including obesity, type 2 diabetes, and cardiovascular disease. This article reviews the concept of metabolic flexibility, its mechanisms, factors affecting it, its role in health and disease, and potential interventions to enhance it. Understanding metabolic flexibility provides insights into optimizing metabolic health through diet, exercise, and pharmacological strategies.