Thiruvasagam P,
Diabetes mellitus (DM) is a major metabolic disorder causing morbidity and mortality worldwide. DM is treated by routine administration of drugs either orally or by injections. Since a hypoglycemic agent causes side effects,there is a growing interest in herbal remedies for the treatment of DM due to fewer side effects. In this research, the leaves extracts of the plant Costusigneus and are subjected to evaluate the anti-diabetic activity, α-amylase inhibition, antioxidant activity and antibacterial activity. The presences of phytochemicals in various extracts of Costus igneus are identified and the anti-diabetic activity was studied in dialysis membrane. Anti-diabetic activity was also carried by α-amylase inhibition study and the result showed that the plant can reduce the blood glucose level. The antioxidant activity was studied by FRAP & DPPH assay and the maximum antioxidant activity was shown by the phytochemicals present in the ethanolic extract.The antibacterial activity was studied by agar well diffusion method and the aqueous extract showed better activity among the extracts. Thus,the Costus igneus leaf extract exhibited good anti-diabetic, antioxidant & antibacterial property and can be used for the treatment of DM and the plant Costus igneus can be treated as herbal plant.