Sheichi Yasuga
Objective: The goal of this study is to look at the diagnostic differences between primary polydipsia (PP) and primary pediatric central diabetes insipidus (PCDI) and provide a rough estimate of the prevalence [1].
Method: From January 2014 to December 2018, we gathered data from 27 patients who presented with polyuria and/or polydipsia as their primary complaints in the Department of Pediatrics at Our University Hospital.
Results: 16 patients were diagnosed with type 1 diabetes mellitus (T1DM), 5 had CDI, 5 had PP, and 1 had nocturnal enuresis. The approximate annual incidence rate for pediatric CDI was 0.71 per 100,000. Body mass index (BMI), morning urine gravity, 24-hour urine volume and intake volume, and bright spots in the posterior pituitary on an MRI were the diagnostic factors. The morning urine gravity cutoff value for CDI was 1.010, with 100% sensitivity and 100% specificity [2]. The end worth of pee volume more than 24 h for CDI was >2299 mL/m2, with a responsiveness of 100% and explicitness of 85.7 %. No pediatric CDI patients had the brilliant spot in the back pituitary of their X-ray, utilizing a sort 1-weighted picture; However, the bright spot was only observed in one out of every four PP patients.
Conclusion: The best guess occurrence of pediatric CDI with polydipsia and polyuria under the restricted condition was 0.71/100,000/year, which was extremely low. Discernable variables between CDI patients and PP patients were BMI, pee and admission volumes north of 24 h, and a brilliant spot on an X-ray. To confirm these findings, additional studies with more patients and multiple institutes are required.