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article de recherche

Dysglycemia and Dyslipidemia Models in Nonhuman Primates: Part V. Diabetic Nephropathy and Effects of Angiotensin Ⅱ Receptor Antagonist Losartan

Jiajun Gao, Xiaoli Wang, Weihua Song, Yixin (Jim) Wang, Yong-Fu Xiao

Long-term hyperglycemia can impair renal microvessels and lead to diabetic nephropathy (DN). Early treatment can delay or prevent its progression. Efficacy of monoclonal antibod..Voir plus»

article de recherche

Galena with B4C high-density heavy concrete for shielding nuclear reactors

Rasoul Mehrnejad*, Abdulhalik Karabulut, Turgay Korkut, Bunyamin Aygun

Shielding of a biological type belonging to a nuclear reactor is considered one of the main issues and the lower complexity and expense of these installations are of important i..Voir plus»

Article de révision

Bile Acids: Mode of Actions on their Nuclear and Membrane Receptors in Initiation of Colorectal Cancer (CRC) besides on Different Modes of Programmed Cell Death: Therapeutic utilization in Treatment of Cancers besides Avoidance of CRC Development: A Narrative Review

Kulvinder Kochar Kaur*, Gautam Nand K Allahbadia, Mandeep Singh

Bile Acids (BAs) possess a considerable significant part in the form of emulsifiers in digestion besides absorption of dietary lipids as well as cholesterol. BAs represent..Voir plus»

article de recherche

Extreme Events Assessment Methodology Coupling Rainfall and TidalLevels in the Coastal Flood Plain of the Sao Paulo North Coast (Brazil) forEngineering Projects Purposes

Alessandro Pezzoli, Diego Lourenco Cartacho, EmiliaArasaki, Paolo Alfredini and Rafael de Oliveira Sakai

The North Coastal Region of the State of São Paulo, which comprises the Municipalities of Caraguatatuba, São Sebastião, Ilhabela and Ubatuba, is one of the most prone to floodin..Voir plus»

Commentaire

Type 2 Diabetes Mellitus- Disease, Diagnosis and Treatment

Yingzheng Zhao, Guangcui Xu, Weidong Wu and Xianwen Yi

Type 2 diabetes mellitus (T2DM) is a fast-growing disease and a leading global public health concern. Multiple complications are associated with T2DM. Patient e..Voir plus»

article de recherche

Cytotoxic Evaluation and DNA Binding Ability of Catalytically Synthesized New Steroidal Lactones

Ashraf Mashrai, Ayaz Mahmood Dar, Shafia Mir, Himanshu Gupta and Shamsuzzaman

In an attempt to find a new class of cytotoxic agents, a series of fused steroidal derivatives containing lactone moiety were prepared via Michael addition reaction of α, ..Voir plus»