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Validation of Next Generation Sequencing Cancer Panels for Clinical Somatic Mutation Profiling-- Identification of Source of Variations and Artifacts using FFPE Tissues

Ken CN Chang*, Yun Zhao, John Kang, Saumya Pant, Ping Qiu, Bo Wei, Russell Weiner and Matthew J Marton

Use of a Next Generation Sequencing (NGS)-based test as a clinical trial assay requires that the test be analytically validated to CLIA/CAP regulations. During the course of ana..Voir plus»

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Investigation of Biofield Treatment on Antimicrobial Susceptibility, Biochemical Reaction Pattern and Biotyping of Enteropathogenic Multidrug-Resistant Escherichia coli Isolates

Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Gopal Nayak, Harish Shettigar, Mayank Gangwar, Snehasis Jana

Study background: Multidrug resistant Escherichia coli (MDR E. coli) has become a major health concern, and failure of treatment leads to huge health burden. Ai..Voir plus»

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Influence of Wasting and Underweight on Malaria Status among Ethiopian Children Aged 6-59 Months: A Facility Based Case Control Study

Hamid Yimam Hassen and Jemal Haidar Ali

Background: Malaria and under-nutrition are among the major causes of childhood mortality in Sub-Saharan Africa including Ethiopia. Although the synergistic rel..Voir plus»

article de recherche

Effects of Smoking on ADPKD: Frequency of Vascular Events and Concentrations of Soluble CD40 Ligand

Jason S Brody, Wei Wang, Robert W Schrier and Berenice Reed-Gitomer

Background: Cardiovascular disease is the leading cause of death among patients with autosomal dominant polycystic kidney disease (ADPKD). Smoking increases inflammation and contri..Voir plus»

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Evaluation of the Prognostic Significance of "High-risk Stigmata" in the International Consensus Guidelines 2012 for Intraductal Papillary Mucinous Neoplasm

Kenjiro Kimura *,Ryosuke Amano ,Sadaaki Yamazoe ,Go Ohira ,Kotaro Miura ,Kohei Nishio ,Katsunobu Sakurai ,Takahiro Toyokawa ,Bunzo Nakata ,Akihiro Murata ,Sadatoshi Shimizu ,Sayaka Tanaka ,Masahiko Ohsawa ,Masaichi Ohira ,Kosei Hirakawa

Study Background: In the International Consensus Guidelines 2012 for intraductal papillary mucinous neoplasm (IPMN), ‘high-ri..Voir plus»

Article de révision

Pneumonic Rehabilitation Improves COPD Outcomes

Lauren M Manzo and Joanie C Jackson

Pulmonary Rehabilitation (PR) is an underutilized service for patients with COPD. This integrative review aims to compile current evidence-based research about the benefits of p..Voir plus»